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Pediatric use of HOCl

01/31/2022 12:22:09 pm

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Fungal infections are common related to the high humidity required for neonates. Pediatric use of HOCl is wide as it can kill microorganisms and fungi, is non-cytotoxic, is safe for use around the eyes, ears, mouth, and genitalia, and has been shown to be safe in children. Small children.

An antimicrobial wound cleanser must be non-cytotoxic, non-toxic if absorbed percutaneously, effective in multiple ways, and painless on application.

A cleansing solution containing hypochlorous acid HOCl as an antimicrobial agent has been added to the wound cleansing regimen in several neonatal and pediatric care practices.

Hypochlorous acid is the preferred option when it comes to preventing and eliminating recurring diaper rashes. Diaper rash is a recurring problem for many babies, children, and the elderly with sensitive skin.

The pH of HOCl intended for wound care is extremely critical, both to the purity of the compound and its ability to achieve clinical efficacy in wound healing.

Hypochlorous acid is known to exist as the desirable antimicrobial, undissociated, neutral preservative compound in a pH range of about 3 to 5; higher pH formulations inevitably become contaminated with sodium hypochlorite, because HOCl begins to break down significantly to hypochlorite anion at pH above 5 or 6. 5-7.

Use in premature babies

Experience with multiple children of various ages, including premature neonates, adds to the growing literature on the successful and safe treatment of various neonatal and pediatric wounds using pure HOCl solution.

Pediatric use of HOCl is considered safe, providing a basis to explore its use. The pH of the skin of a premature baby is 5.6. Pure hypochlorous acid has a pH of 5.1-5.6, making it an ideal agent for use in premature infants.

Fountain:

https://www.marwocn.org/conference/2017Conf/posters/Elsass-vashe.pdf

https://www.o-wm.com/article/hypochlorous-acid-pediatric-wound-management-cleansing-healing-wounds

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